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Cat. No. Product Name Target Signaling Pathways
T79750 TLR7 agonist 15

TLR7 agonist15(compound 16b)作为一种高效的TLR7激动剂,其EC50值为59 nM。在低纳摩尔浓度下,该化合物能够有效诱导小鼠巨噬细胞和hPBMC的激活。
T74468 MC-Val-Cit-PAB-Amide-TLR7 agonist 4

MC-Val-Cit-PAB-Amide-TLR7 agonist 4 (example 15) 是一种 HER2-TLR7和 HER2-TLR8免疫激动剂复合物。
T61601 TLR7/8 antagonist 2

TLR7/8 antagonist 2 (Compound 15) is a highly potent and orally active agonist of TLR7/8, exhibiting IC50 values of 4.9 and 0.6 nM for TLR7 and TLR8, respectively. Its strong affinity for these receptors makes it a promising candidate for the treatment and investigation of autoimmune diseases, including lupus erythematosus, which is associated with inappropriate activation of TLR7 and TLR8. Consequently, TLR7/8 antagonist 2 represents a valuable tool for research in the field of autoimmune disea...

化合物

TLR7 agonist 15
Cat.No: T79750
Synonym:
Target:
MC-Val-Cit-PAB-Amide-TLR7 agonist 4
Cat.No: T74468
Synonym:
Target:
TLR7/8 antagonist 2
Cat.No: T61601
Synonym:
Target:
TargetMol Loading
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