Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T8503 |
TLR4-IN-C34
|
TLR | Immunology/Inflammation |
TLR4-IN-C34 是 TLR4 的抑制剂,可减少内毒素血症和坏死性小肠结肠炎模型中的全身炎症 | |||
T38547 |
TLR4-IN-C34-C2-COOH
TLR4-IN-C34-C2-COOH |
||
TLR4-IN-C34-C2-COO is a linker compound that incorporates TLR4 inhibitor TLR4-IN-C34. It effectively inhibits TLR4 activity in enterocytes and macrophages. Moreover, it demonstrates a notable ability to mitigate systemic inflammation in murine models of endotoxemia and necrotizing enterocolitis. |