Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPJ-01067 |
TFIIB Protein, Human, Recombinant (GST)
TFIIB,GTF2B,TF2B,S300-II,General Transcription Fact... |
Human | E. coli |
Transcription Initiation Factor IIB (TFIIB) is an essential factor for transcription by RNA Polymerase II. TFIIB localizes to the nucleus where it forms a complex (the DAB complex) with transcription factor IID and IIA. TFIIB plays a role as a bridge between IID, which initially recognizes the promoter sequence, and RNA polymerase II. TFIIB is involved in the selection of transcription start site. | |||
TMPH-00536 |
Epstein-Barr virus (strain AG876) EBNA2 Protein (His & Myc)
|
EBV | P. pastoris (Yeast) |
Plays a key role in the activation of the host resting B-cell and stimulation of B-cell proliferation. Acts by up-regulating the expression of viral EBNA1-6, LMP1, LMP2A and LMP2B genes, as well as several host genes including CD21, CD23 and MYC. Activates transcription by acting as an adapter molecule that binds to cellular sequence-specific DNA-binding proteins such as host CBF1, SMARCB1 and SPI1. Once EBNA2 is near promoter sites, its acidic activating domain recruits basal and activation-ass... |