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抑制剂 & 化合物

2

重组蛋白

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Cat. No. Product Name Target Signaling Pathways
T68538 CEP-14083

CEP-14083 is a potent ALK inhibitor that has shown activity in an NPM/ALK–carrying T-cell lymphoma in vitro study. Presumably, this compound binds to the hinge region of the kinase in an ATP-competitive manner. CEP-14083 displays a potent activity against ALK in enzymatic assays (IC50 = 11 nmol/L). Further, CEP-14083 is also able to inhibit the insulin receptor at a concentration within a nanomolar range. In a preclinical assay, CEP-14083 showed that, via NPM/ALK TK inhibition, it could control...

化合物

CEP-14083
Cat.No: T68538
Synonym:
Target:
Cat. No. Product Name Species Expression System
TMPY-01059 BMPR2 Protein, Human, Recombinant (His)

POVD1,PPH1,BMPR3,BRK-3,BMPR-II,bone morphogenetic p...

Human HEK293 Cells
BMPR2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 15.6 kDa and the accession number is Q13873.
TMPY-00683 BMPR2 Protein, Human, Recombinant (His & hFc)

BMPR3,BRK-3,PPH1,BMPR-II,bone morphogenetic pro...

Human HEK293 Cells
BMPR2 Protein, Human, Recombinant (His & hFc) is expressed in HEK293 mammalian cells with His and hFc tag. The predicted molecular weight is 42 kDa and the accession number is Q13873.

重组蛋白

BMPR2 Protein, Human, Recombinant (His)
Cat.No: TMPY-01059
Species: Human
Expression System: HEK293 Cells
BMPR2 Protein, Human, Recombinant (His & hFc)
Cat.No: TMPY-00683
Species: Human
Expression System: HEK293 Cells
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