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Cat. No. Product Name Target Signaling Pathways
T71483 Streptonigrin (racemate)

Streptonigrin is an aminoquinone antitumor and antibacterial antibiotic produced by Streptomyces flocculus. Streptonigrin inhibits β-Catenin/Tcf signaling and shows cytotoxicity in β-catenin-activated cells. Streptonigrin induces delayed chromosomal instability involving interstitial telomeric sequences in Chinese hamster ovary cells. Note: Streptonigrin from natural resource is (-)-rotation, has CAS#3930-19-6 and is a R-isomer.
T25798 Methyl Streptonigrin

NSC 45384,NSC45384,NSC-45384

Methyl Streptonigrin is an ABCG2 transporter function inhibitor.
T35607 10'-Desmethoxystreptonigrin

10'-Desmethoxystreptonigrin is an antibiotic originally isolated from Streptomyces and a derivative of the antibiotic streptonigrin. It is active against a variety of bacteria, including S. aureus, S. faecalis, E. coli, K. pneumoniae, and P. vulgaris (MICs = 0.4, 1.6, 3.1, 3.1 and 0.4 μg/ml, respectively). 10'-Desmethoxystreptonigrin is cytotoxic to HCT116 colon and A2780 ovarian cancer cells (IC50s = 0.004 and 0.001 μg/ml, respectively), as well as HCT116 cells resistant to etoposide and tenipo...

化合物

Streptonigrin (racemate)
Cat.No: T71483
Synonym:
Target:
Methyl Streptonigrin
Cat.No: T25798
Synonym: NSC 45384,NSC45384,NSC-45384
Target:
10'-Desmethoxystreptonigrin
Cat.No: T35607
Synonym:
Target:
Cat. No. Product Name Target Signaling Pathways
T16946 Streptonigrin

Bruneomycin

Others Others
Streptonigrin is a natural product produced by Streptomyces flocculus, has both anti-tumor and anti-bacterial activity. Streptonigrin acts as a pan-PAD inhibitor (IC50s: 48.3±34.2 µM, 26.1±0.3 µM, 0.43±0.03 µM, and 2.5±0.4 µM for PAD1, PAD2, PAD3, and PAD

天然产物

Streptonigrin
Cat.No: T16946
Synonym: Bruneomycin
Target: Others
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