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Targets Recommended: Antibacterial

12

抑制剂 & 化合物

1

天然产物

4

重组蛋白

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Cat. No. Product Name Target Signaling Pathways
T41032 Lysostaphin

Antibacterial Microbiology/Virology
Lysostaphin是一种具有强大抗葡萄球菌活性的化合物,通过三种不同的酶展现其酶促活性:glycylglycine endopeptidase、endo-β-N-acetyl glucosamidase和N-acetyl muramyl-L-alanine amidase。
T35005 Usistapide

R-256918,JNJ-16269110,JNJ16269110,R256918,JNJ 16269110,R 256918

UsISpide(JNJ-16269110 R256918) is an inhibitor of microsomal triglyceride transfer protein (MTTP) under development for the treatment of obesity and type 2 diabetes.
TP2455 Locustapyrokinin II

Pglu-ser-val-pro-thr-phe-thr-pro-arg-leu-NH2

Locustapyrokinin II is a member of the FXPRL-amide peptide family isolated from Locusta migratoria.
T81098 Stapokibart

CM310

Stapokibart (CM310) 是一款针对IL-4Rα的人源化单克隆抗体,有效抑制IL-4及IL-13与该受体亚基的结合。该药物对人类、食蟹猴和大鼠的IL-4Rα都有作用。
T34393 Rostaporfin

SnET2,tin etiopurpurin dichloride,tin ethyl etiopurpurin dichloride,Purlytin,Sn(IV) etiopurpurin

Rostaporfin (also known as REM-001, tin ethyl etiopurpurin, Sn(IV) etiopurpurin, Purlytin, SnET2), is a synthetic purpurin with photosensitizing activity. Rostaporfin preferentially accumulates in tumor cells due to an increased rate of metabolism. Upon e
T62665 Antistaphylococcal agent 2

Antistaphylococcal agent 2 是一种抗葡萄球菌的治疗剂。
T80707 α-Hemolysin (Staphylococcus aureus)

α-Hemolysin (Staphylococcus aureus) 是一种由金黄色葡萄球菌分泌的毒力因子,具有破坏宿主细胞质膜的多肽特性。α-Hemolysin 绑定细胞表面后,通过其单体组装成同型七聚体预孔结构,并转变为成熟的跨膜孔,形成水通道。这一过程促使 K+ 和 Ca2+ 离子通过膜,触发靶细胞的坏死性死亡。
T39583 Zastaprazan

Zastaprazan, a proton pump inhibitor (WO2018008929), is utilized in the research of gastrointestinal inflammatory diseases and conditions related to gastric acid.
T39886 Antistaphylococcal agent 3

Antistaphylococcal agent 3 is an antistaphylococcal therapeutic agent.
T61855 Antistaphylococcal agent 1

Antistaphylococcal agent 1 是一种抗葡萄球菌的治疗剂。
T32079 Histapyrrodine hydrochloride

Histapyrrodine hydrochloride is a bioactive chemical.
T28732 SCH-538415

SCH-538415 is an inhibitor of acyl carrier protein synthase from a microorganism. SCH-538415 exhibited inhibitory activity in the acyl carrier protein synthase (AcpS) assay with an IC(50) value of 4.19 microM and showed antibacterial activity against Stap

化合物

Lysostaphin
Cat.No: T41032
Synonym:
Target: Antibacterial
Usistapide
Cat.No: T35005
Synonym: R-256918,JNJ-16269110,JNJ16269110,R256918,JNJ 16269110,R 256918
Target:
Locustapyrokinin II
Cat.No: TP2455
Synonym: Pglu-ser-val-pro-thr-phe-thr-pro-arg-leu-NH2
Target:
Stapokibart
Cat.No: T81098
Synonym: CM310
Target:
Rostaporfin
Cat.No: T34393
Synonym: SnET2,tin etiopurpurin dichloride,tin ethyl etiopurpurin dichloride,Purlytin,Sn(IV) etiopurpurin
Target:
Antistaphylococcal agent 2
Cat.No: T62665
Synonym:
Target:
α-Hemolysin (Staphylococcus aureus)
Cat.No: T80707
Synonym:
Target:
Zastaprazan
Cat.No: T39583
Synonym:
Target:
Antistaphylococcal agent 3
Cat.No: T39886
Synonym:
Target:
Antistaphylococcal agent 1
Cat.No: T61855
Synonym:
Target:
Histapyrrodine hydrochloride
Cat.No: T32079
Synonym:
Target:
SCH-538415
Cat.No: T28732
Synonym:
Target:
Cat. No. Product Name Target Signaling Pathways
T81099 Staphyloferrin A

Staphyloferrin A,一种铁载体蛋白,与抗生素结合对抗抗药性细菌性皮肤病进行研究。

天然产物

Staphyloferrin A
Cat.No: T81099
Synonym:
Target:
Cat. No. Product Name Species Expression System
TMPH-03275 Cytoglobin Protein, Rat, Recombinant (His & Myc)

Stellate cell activation-associated protein,Stap,CY...

Rat E. coli
May have a protective function during conditions of oxidative stress. May be involved in intracellular oxygen storage or transfer. Plays a role in the development of liver fibrosis. Has a peroxidase activity.
TMPJ-01248 Cytoglobin/CYGB Protein, Human, Recombinant (His)

Stellate Cell Activation-Associated Protein,Cytoglobin,CYGB,...

Human E. coli
Cytoglobin is a ubiquitously globin protein that belongs to the globin family. The highest expressed in heart, stomach, bladder and small intestine. CYGB acts a protector under conditions of oxidative stress. CYGB may be involved in intracellular oxygen storage or transfer, modulates oxygen and nitric oxide metabolism or scavenging free radicals within a cell.
TMPH-03576 Staphopain A Protein, S. aureus, Recombinant (His & Myc)

Staphylococcus aureus E. coli
Staphopain A Protein, S. aureus, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 27.4 kDa and the accession number is P81297.
TMPH-03577 Staphopain B Protein, S. aureus, Recombinant (GST)

Staphylococcus aureus E. coli
Cysteine protease that plays an important role in the inhibition of host innate immune response. Degrades host elastin, fibrogen, fibronectin and kininogen. Blocks phagocytosis of opsonised S. aureus by neutrophils and monocytes by inducing their death in a proteolytic activity-dependent manner. Decreases surface expression of the 'don't eat me' signal CD31 on neutrophils. Cleaves host galectin-3/LGALS3, thereby inhibiting the neutrophil-activating ability of the lectin. Staphopain B Protein, S....

重组蛋白

Cytoglobin Protein, Rat, Recombinant (His & Myc)
Cat.No: TMPH-03275
Species: Rat
Expression System: E. coli
Cytoglobin/CYGB Protein, Human, Recombinant (His)
Cat.No: TMPJ-01248
Species: Human
Expression System: E. coli
Staphopain A Protein, S. aureus, Recombinant (His & Myc)
Cat.No: TMPH-03576
Species: Staphylococcus aureus
Expression System: E. coli
Staphopain B Protein, S. aureus, Recombinant (GST)
Cat.No: TMPH-03577
Species: Staphylococcus aureus
Expression System: E. coli
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