Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPJ-01064 |
Serpin G1 Protein, Mouse, Recombinant (His)
Serping1,Plasma protease C1 inhib... |
Mouse | HEK293 Cells |
SERPIN G1 is a member of the serpin family, The C-terminal serpin domain is similar to other serpins, and this part of C1-INH provides the inhibitory activity. SERPIN G1 is involved in the inhibition of the complement system to prevent spontaneous activation. SERPIN G1 may play a potentially crucial role in regulating important physiological pathways including complement activation, blood coagulation, fibrinolysis and the generation of kinins. SERPIN G1 prevents the proteolytic cleavage of later... | |||
TMPJ-00502 |
Serpin G1 Protein, Human, Recombinant (His)
C1-Inhibiting Factor,Serpin G1,SERPING... |
Human | HEK293 Cells |
As protease inhibitors, serpins have an array of functions including regulating blood clotting, the complement pathway, extracellular matrix remodeling, and cell motility. Serpin G1 is a serine protease inhibitor protein. It is the largest member among the serpin class of proteins. Remarkably, Serpin G1 has a 2-domain structure, unlike most family members. The C-terminal serpin domain is similar to other serpins, and this part of Serpin G1 provides the inhibitory activity. The N-terminal domain ... | |||
TMPH-00672 |
Metalloprotease stcE Protein, E. coli O157:H7, Recombinant (His)
|
E. coli | E. coli |
Virulence factor that contributes to intimate adherence of enterohemorrhagic E.coli (EHEC) O157:H7 to host cells. Is able to cleave the secreted human mucin 7 (MUC7) and the glycoprotein 340 (DMBT1/GP340). Also cleaves human C1 inhibitor (SERPING1), a regulator of multiple inflammatory pathways, and binds and localizes it to bacterial and host cell surfaces, protecting them from complement-mediated lysis. Therefore, the current model proposes two roles for StcE during infection: it acts first as... |