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Cat. No. Product Name Target Signaling Pathways
T8395 Nomegestrol acetate

Others; Progesterone Receptor Others
Nomegestrol acetate 是一种孕酮受体的完全激动剂,是一种高选择性孕激素。
T3538 Sufugolix

TAK-013

LHRH Endocrinology/Hormones
Sufugolix (TAK-013) 是一种高效的、有口服活性的黄体激素释放激素(LHRH) 受体拮抗剂(IC50:0.1 nM)。
T68861 MS-0022

MS-0022 is a SMO antagonist. MS-0022 showed effective Hh signaling pathway inhibition at the level of SMO in the low nM range, and Hh pathway inhibition downstream of Suppressor of fused (SUFU) in the low µM range. MS-0022 reduced growth in the tumor cell lines PANC-1, SUIT-2, PC-3 and FEMX in vitro. MS-0022 is a treatment led to a transient delay of tumor growth that correlated with a reduction of stromal Gli1 levels in SUIT-2 xenografts in vivo.

化合物

Nomegestrol acetate
Cat.No: T8395
Synonym:
Target: Others, Progesterone Receptor
Sufugolix
Cat.No: T3538
Synonym: TAK-013
Target: LHRH
MS-0022
Cat.No: T68861
Synonym:
Target:
TargetMol Loading
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