Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-03456 |
SRFBP1 Protein, Human, Recombinant (His & GST)
STRAP,BUD22,P49,serum response factor binding prote... |
Human | Baculovirus Insect Cells |
SRFBP1 contains 7 WD repeats and belongs to the WD repeat STRAP family. SRFBP1 may play a role in the cellular distribution of the SMN complex. The SMN complex plays an essential role in spliceosomal snRNP assembly in the cytoplasm and is required for pre-mRNA splicing in the nucleus. SRFBP1 negatively regulates TGF-beta signaling but positively regulates the PDPK1 kinase activity by enhancing its autophosphorylation and by significantly reducing the association of PDPK1 with 14-3-3 protein. SRF... |