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Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T38835 |
STK33-IN-1
STK33-IN-1 |
||
STK33-IN-1 (compound 1) is a STK33 inhibitor, with an IC 50 of 7 nM. | |||
T9993 |
SBP-3264
|
Others | Others |
SBP-3264是一种常用于研究急性髓性白血病中 STK3和 STK4左右价值的化学探针。 |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-04424 |
MST3 Protein, Human, Recombinant (His)
HEL-S-95,STE20,MST3B,RP11-111L24.5,MST3, |
Human | Baculovirus Insect Cells |
Aberrant STK24 expression was an independent prognostic indicator in lung adenocarcinoma patients. Its dysregulation was associated with its DNA copy number alteration and methylation. STK24/CCM3-regulated exocytosis plays an important role in the protection of kidneys from ischemia-reperfusion injury. | |||
TMPH-02087 |
STK38L Protein, Human, Recombinant (His)
|
Human | E. coli |
Involved in the regulation of structural processes in differentiating and mature neuronal cells. STK38L Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 33.5 kDa and the accession number is Q9Y2H1. | |||
TMPH-03764 |
YAP1 Protein, Human, Recombinant (His)
YAP1-2gamma,YAP2L,YAP65 |
Human | P. pastoris (Yeast) |
Transcriptional regulator which can act both as a coactivator and a corepressor and is the critical downstream regulatory target in the Hippo signaling pathway that plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein STK3/MST2 and STK4/MST1, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1,... |