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8

抑制剂 & 化合物

2

重组蛋白

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Cat. No. Product Name Target Signaling Pathways
T39741 SSAO inhibitor-1

SSAO inhibitor-1 is a compound that acts as an inhibitor of semicarbazide-sensitive amine oxidase (SSAO). It exhibits anti-inflammatory properties and is commonly employed in research pertaining to liver diseases.
T60640 SSAO inhibitor-2

SSAO inhibitor-2 (Compound 1) 可用于动脉粥样硬化、糖尿病及其并发症、肥胖、中风、慢性肾病、视网膜病变、慢性阻塞性肺病 (COPD)、自身免疫性疾病、多发性硬化等的研究。SSAO inhibitor-2 是氨基脲敏感性胺氧化酶 (SSAO) 抑制剂,其对人 SSAO 和 MAO-A 的IC50分别为 <10 nM 和 10-100 μM。
T60909 SSAO inhibitor-3

SSAO inhibitor-3 (Compound 2) 可用于研究动脉粥样硬化、糖尿病及其并发症、肥胖症、中风、慢性肾病、视网膜病变、慢性阻塞性肺病 (COPD)、自身免疫性疾病、多发性硬化等。SSAO inhibitor-3 是一种氨基脲敏感性胺氧化酶 (SSAO) 的抑制剂,对人 AOC1 和SSAO 的IC50分别为 0.1-10 μM 和 <10 nM 。
T61133 SSAO/VAP-1 inhibitor 1

SSAO/VAP-1 inhibitor 1 是一种有效的SSAO/VAP-1抑制剂。SSAO/VAP-1 促进葡萄糖转运 4 (GLUT 4) 从脂肪细胞转移到细胞膜,从而调节葡萄糖转运。在内皮细胞中,SSAO/VAP-1 可以介导白细胞和内皮细胞的粘附和渗出,并参与炎症反应。SSAO/VAP-1 inhibitor 1 具有研究炎症和/或炎症相关疾病或糖尿病和/或糖尿病相关疾病的潜力。
T26795 PXS-4728A

BI-1467335,BI 1467335,BI1467335,BI-1467335 HCl

Monoamine Oxidase Neuroscience
BI-1467335 HCl(BI 1467335) 是口服具有活性的、选择性的氨基脲敏感性胺氧化酶(SSAO) 抑制剂。PXS-4728A (BI 1467335) 能够改善小鼠的慢性阻塞性肺疾病。
T38966 PXS-4681A

PXS-4681A is a powerful, specific, and irreversible inhibitor of semicarbazide-sensitive amine oxidase (SSAO; VAP-1), with an oral activity and a Ki value of 37 nM. It exhibits exceptional selectivity towards related amine oxidases, ion channels, and seven-transmembrane domain receptors. Additionally, PXS-4681A demonstrates potent anti-inflammatory properties.
T33265 MDL-72274 HCl

MDL 72274A,MDL72274,MDL-72274,MDL-72274A,MDL72274A,MDL 72274

MDL-72274 HCl is a selective and effective inhibitor of SSAO for the treatment of Parkinson's disease.
T68785 MD 220661

MD 220661 is an inhibitor of semicarbazide-sensitive amine oxidase (SSAO), and a substrate of the enzyme.

化合物

SSAO inhibitor-1
Cat.No: T39741
Synonym:
Target:
SSAO inhibitor-2
Cat.No: T60640
Synonym:
Target:
SSAO inhibitor-3
Cat.No: T60909
Synonym:
Target:
SSAO/VAP-1 inhibitor 1
Cat.No: T61133
Synonym:
Target:
PXS-4728A
Cat.No: T26795
Synonym: BI-1467335,BI 1467335,BI1467335,BI-1467335 HCl
Target: Monoamine Oxidase
PXS-4681A
Cat.No: T38966
Synonym:
Target:
MDL-72274 HCl
Cat.No: T33265
Synonym: MDL 72274A,MDL72274,MDL-72274,MDL-72274A,MDL72274A,MDL 72274
Target:
MD 220661
Cat.No: T68785
Synonym:
Target:
Cat. No. Product Name Species Expression System
TMPJ-00379 AOC3 Protein, Human, Recombinant (hFc)

SSAO,AOC3,Membrane primary amine oxidase,Copper ami...

Human HEK293 Cells
Membrane primary amine oxidase(AOC3), also known as vascular adhesion protein (VAP-1) and HPAO, this protein is a member of the semicarbazide-sensitive amine oxidase (SSAO) family. VAP-1 is a type 1 membrane-bound glycoprotein that has a distal adhesion domain and an enzymatically active amine oxidase site outside of the membrane, VAP-1 has adhesive properties, functional monoamine oxidase activity, and possibly plays a role in glucose handling, leukocyte trafficking, and migration during inflam...
TMPJ-00380 AOC3 Protein, Human, Recombinant (His)

Membrane primary amine oxidase,HPAO,VAP-1,Semicarbazide-sens...

Human HEK293 Cells
Vascular adhesion protein-1(VAP-1) is a copper amine oxidase with a topaquinone cofactor.VAP-1 is a type II integral membrane protein, but a soluble form of the enzyme is present in human serum, and its level increases in diabetes and some inflammatory liver diseases. VAP-1 catalyzes the oxidative deamination of small primary amines such as methylamine, benzylamine, and aminoacetone in a reaction that produces an aldehyde, ammonia, and H2O2. VAP-1 vascular expression is regulated at sites of inf...

重组蛋白

AOC3 Protein, Human, Recombinant (hFc)
Cat.No: TMPJ-00379
Species: Human
Expression System: HEK293 Cells
AOC3 Protein, Human, Recombinant (His)
Cat.No: TMPJ-00380
Species: Human
Expression System: HEK293 Cells
TargetMol Loading
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