Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-03847 |
FRZB Protein, Human, Recombinant (His)
frizzled-related protein,FRITZ,OS1,SFRP3,FRZB-PEN,F... |
Human | HEK293 Cells |
FRZB also known as sFRP-3, is a secreted protein containing a domain similar to the putative Wnt-binding region of the frizzled family of transmembrane receptors. FRZB is widely expressed in adult mammalian tissues. In the Xenopus gastrula, FRZB is regulated as a typical Spemann organizer component. FRZB also functions as a competitor for the cell-surface G-protein receptor Frizzled. It is espically important in embryonic development. Defects in FRZB gene can cause female-specific osteoarthritis... |