Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-00163 |
SPINK2 Protein, Human, Recombinant (hFc)
serine peptidase inhibitor, Kazal type 2 (acrosin-t... |
Human | HEK293 Cells |
Human serine proteinase inhibitor Kazal-type 2 (SPINK2) functions as a trypsin/acrosin inhibitor and is synthesized mainly in the testis and seminal vesicle where its activity is engaged in fertility. The SPINK2 protein contains a typical Kazal domain composed by six cysteine residues forming three disulfide bridges. The expression of SPINK2 is closely related to cancer such as lymphomas, in that a high transcript level of SPINK2 in patients with primary cutaneous follicle center cell lymphomas ... | |||
TMPH-02898 |
SPINK2 Protein, Mouse, Recombinant (His & Myc)
|
Mouse | E. coli |
As a strong inhibitor of acrosin, it is required for normal spermiogenesis. It probably hinders premature activation of proacrosin and other proteases, thus preventing the cascade of events leading to spermiogenesis defects. May be involved in the regulation of serine protease-dependent germ cell apoptosis. It also inhibits trypsin. SPINK2 Protein, Mouse, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 15.0 kDa and ... |