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Cat. No.	Product Name	Target	Signaling Pathways
T6741	SPDP SPDP Crosslinker	Others	Others
	SPDP 是一种短链交联剂，用于通过 NHS 酯和吡啶基二硫醇反应基团与半胱氨酸巯基形成可切割（可还原）的二硫键，实现胺与巯基的共轭。它是一种可降解的 ADC 连接剂，可用于合成抗体偶联药物。
T38597	SPDP-sulfo
	SPDP-sulfo is a cleavable linker vital in ADC synthesis. SPDP-sulfo joins cytotoxic drugs to antibodies, enabling precise delivery to cells or proteins. The cleavable nature ensures controlled drug release, optimizing ADC effectiveness.
T17834	DM4-SPDP	Others	Others
	DM4-SPDP, a drug-linker conjugate, integrates the antitubulin agent DM4 with the linker SMCC, facilitating the creation of antibody drug conjugates[1]. Additionally, SPDP serves as a short-chain crosslinker enabling amine-to-sulfhydryl conjugation, leveraging NHS-ester and pyridyldithiol groups to establish cleavable (reducible) disulfide bonds with cysteine sulfhydryls[2][3].
T18535	PEG4-SPDP	Others	Others
	PEG4-SPDP is a cleavable ADC linker used for the antibody-drug conjugates (ADCs).
T18709	SPDP-PEG12-acid	Others	Others
	SPDP-PEG12-acid is a cleavable 12-unit polyethylene glycol (PEG) linker utilized for the synthesis of antibody-drug conjugates (ADCs)[1].
T18711	SPDP-PEG24-acid	Others	Others
	SPDP-PEG24-acid is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
T18716	SPDP-PEG9-acid	Others	Others
	SPDP-PEG9-acid is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
T16916	SPDP-PEG4-acid	Others	Others
	SPDP-PEG4-acid is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
T18713	SPDP-PEG36-NHS ester	Others	Others
	SPDP-PEG36-NHS ester is a PEG ADC linker consisting of 36 units, characterized by cleavability. It plays a crucial role in the synthesis of antibody-drug conjugates (ADCs)[1].
T18725	Sulfo-LC-SPDP	Others	Others
	Sulfo-LC-SPDP is a heterobifunctional crosslinker characterized by its thiol-cleavable and membrane impermeable properties.
T15724	LC-PEG8-SPDP	Others	Others
	LC-PEG8-SPDP is a cleavable ADC linker used for the antibody-drug conjugates (ADCs)[1].
T18715	SPDP-PEG7-acid	Others	Others
	SPDP-PEG7-acid is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
T18714	SPDP-PEG5-acid	Others	Others
	SPDP-PEG5-acid is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
T16915	SPDP-C6-NHS ester	Others	Others
	SPDP-C6-NHS ester is an alkyl/ether-based linker utilized in the synthesis of PROTACs[1].
T18710	SPDP-PEG12-NHS ester	Others	Others
	SPDP-PEG12-NHS ester is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
T18712	SPDP-PEG24-NHS ester	Others	Others
	SPDP-PEG24-NHS ester is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
T16917	SPDP-PEG4-NHS ester	Others	Others
	SPDP-PEG4-NHS ester is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
T16918	SPDP-PEG6-NHS ester	Others	Others
	SPDP-PEG6-NHS ester is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
T18525	PC SPDP-NHS carbonate ester	Others	Others
	PC SPDP-NHS carbonate ester is a cleavable linker compound utilized in the synthesis of antibody-drug conjugates (ADCs)[1].
T18708	SPDP-C6-Gly-Leu-NHS ester	Others	Others
	SPDP-C6-Gly-Leu-NHS ester is a cleavable linker employed in the synthesis of antibody-drug conjugates (ADCs)[1].
T18733	Sulfo-SPDP-C6-NHS sodium	Others	Others
	Sulfo-SPDP-C6-NHS sodium is a sodium salt form of a cleavable ADC linker employed in the synthesis of antibody-drug conjugates (ADCs)[1].
T77286	DSPE-SPDP
	DSPE-SPDP，一种磷脂分子，能够在水中自行定向并形成脂质双层，适用于多种生化研究。
T33904	PDPH Crosslinker PDPH Cross linker,SPDP Hydrazide,PDPH Cross-linker
	PDPH crosslinker(SPDP Hydrazide) is a lytic heterobisfunctional protein crosslinker.
T18702	DBA-DM4	Others	Others
	DBA-DM4 is a drug-linker conjugate for antibody-drug conjugate (ADC) synthesis, combining the tubulin inhibitor DM1 with the SPDP linker[1].

化合物

Cat.No: T6741

Synonym: SPDP Crosslinker

Target: Others

Cat.No: T38597

Cat.No: T17834

Target: Others

Cat.No: T18535

Target: Others

SPDP-PEG12-acid

Cat.No: T18709

Target: Others

SPDP-PEG24-acid

Cat.No: T18711

Target: Others

SPDP-PEG9-acid

Cat.No: T18716

Target: Others

SPDP-PEG4-acid

Cat.No: T16916

Target: Others

SPDP-PEG36-NHS ester

Cat.No: T18713

Target: Others

Sulfo-LC-SPDP

Cat.No: T18725

Target: Others

Cat.No: T15724

Target: Others

SPDP-PEG7-acid

Cat.No: T18715

Target: Others

SPDP-PEG5-acid

Cat.No: T18714

Target: Others

SPDP-C6-NHS ester

Cat.No: T16915

Target: Others

SPDP-PEG12-NHS ester

Cat.No: T18710

Target: Others

SPDP-PEG24-NHS ester

Cat.No: T18712

Target: Others

SPDP-PEG4-NHS ester

Cat.No: T16917

Target: Others

SPDP-PEG6-NHS ester

Cat.No: T16918

Target: Others

PC SPDP-NHS carbonate ester

Cat.No: T18525

Target: Others

SPDP-C6-Gly-Leu-NHS ester

Cat.No: T18708

Target: Others

Sulfo-SPDP-C6-NHS sodium

Cat.No: T18733

Target: Others

Cat.No: T77286

PDPH Crosslinker

Cat.No: T33904

Synonym: PDPH Cross linker,SPDP Hydrazide,PDPH Cross-linker

Cat.No: T18702

Target: Others

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