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Cat. No. Product Name Target Signaling Pathways
T18701 SPDB-DM4

Others Others
SPDB-DM4 is a drug-linker conjugate designed for antibody-drug conjugate (ADC) applications, employing the maytansine-based payload DM4 (a tubulin inhibitor) connected through a SPDB linker. This compound demonstrates significant anti-tumor efficacy.
T38682 Lys-Nε-SPDB-DM4

Lys-Nε-SPDB-DM4

Lys-Nε-SPDB-DM4 is a drug-linker conjugate composed of a potent a tubulin inhibitor DM4 and a linker Lys-Nε-SPDB to make antibody drug conjugate (ADC).
T18730 sulfo-SPDB-DM4

Others Others
Sulfo-SPDB-DM4 is a drug-linker conjugate designed for antibody-drug conjugates (ADCs) that employs the maytansine-based payload (DM4, an antitubulin agent) connected through the sulfo-SPDB linker.
T77907 Tusamitamab ravtansine

HuMAb2-3-SPDB-DM4,SAR-408701

Tusamitamab ravtansine (SAR-408701) 是一款针对CEACAM5的人源化单克隆抗体与DM4细胞毒性药物经活性分子连接而成的抗体-药物偶联物(ADC),专门靶向CEACAM5表达的肿瘤细胞。
T4346 SPDB

Others Others
SPDB 是一种可降解的 ADC 连接剂,可用于合成抗体偶联药物。它是一个与 DM4 偶联物相连的小片段,利用二硫键与抗体偶联。

化合物

SPDB-DM4
Cat.No: T18701
Synonym:
Target: Others
Lys-Nε-SPDB-DM4
Cat.No: T38682
Synonym: Lys-Nε-SPDB-DM4
Target:
sulfo-SPDB-DM4
Cat.No: T18730
Synonym:
Target: Others
Tusamitamab ravtansine
Cat.No: T77907
Synonym: HuMAb2-3-SPDB-DM4,SAR-408701
Target:
SPDB
Cat.No: T4346
Synonym:
Target: Others
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