Cat. No. | Product Name | Target | Signaling Pathways |
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T71295 |
SOR-C13
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SOR-C13 is an inhibitor of transient receptor potential cation channel vanilloid family member 6 (TRPV6, CaT1 or CATL) with potential antineoplastic activity. TRPV6 calcium channel inhibitor SOR-C13 binds to TRPV6 and prevents the influx of calcium ions into TRPV6-expressing tumor cells. This inhibits the activation of nuclear factor of activated T-cell (NFAT) transcription complex which may result in an inhibition of calcium-dependent cancer cell proliferation and an induction of apoptosis in t... | |||
T75995 |
SOR-C13 TFA
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SOR-C13 TFA,一种羧基末端截短肽,是一种高亲和力的 TRPV6拮抗剂,IC50值为 14 nM。TRPV6 是一种非电压门控钙通道,与乳腺癌的恶性肿瘤和预后不良有关。SOR-C13 TFA 具有抗癌活性。 |