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Cat. No. Product Name Target Signaling Pathways
T7263 SMS2-IN-2

SMS2 inhibitors

Others Others
SMS2-IN-2 (SMS2 inhibitors) 是一种具有高度选择性、口服具有活力的鞘磷脂合成酶 2 抑制剂,能够作用于 SMS2 (IC50:100 nM)和 SMS1 (IC50:56 nM)。它可减轻慢性炎症反应。
T12938 SMS2-IN-1

Others Others
SMS2-IN-1 是一种有效且具有高选择性的鞘磷脂合成酶 2 (SMS2) 抑制剂, IC50 为 6.5 nM,Kd 为 37 nM。SMS2-IN-1 对 SMS2 的选择性比 SMS1 (IC50 为 1000 nM) 多 150 倍。
T37953 Sphingomyelins (buttermilk)

Sphingomyelins (SMs) are bioactive sphingolipids found in mammalian cell membranes.1SMs make up 2-15% of the total organ phospholipid population but are found at higher concentrations in the brain and myelin sheaths surrounding peripheral nerves. They interact with cholesterol to control its distribution within cellular membranes and maintain cholesterol homeostasis in cells. SMs undergo hydrolysis by sphingomyelinase to form ceramides, which are sphingolipid mediators of intracellular signaling...

化合物

SMS2-IN-2
Cat.No: T7263
Synonym: SMS2 inhibitors
Target: Others
SMS2-IN-1
Cat.No: T12938
Synonym:
Target: Others
Sphingomyelins (buttermilk)
Cat.No: T37953
Synonym:
Target:
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