Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-05835 |
Siglec-15 Protein, Mouse, Recombinant (rFc)
Cd33l3,SIGLEC-I,EG620235,si |
Mouse | HEK293 Cells |
Siglec-15 Protein, Mouse, Recombinant (rFc) is expressed in HEK293 mammalian cells with rFc tag. The predicted molecular weight is 50.83 kDa and the accession number is A7E1W8. | |||
TMPJ-00225 |
Siglec-15 Protein, Mouse, Recombinant (His)
Siglec-15,Sialic aci... |
Mouse | HEK293 Cells |
Human Siglec-15 is a transmembrane glycoprotein in the Siglec family. Siglecs are type I transmembrane proteins where the NH3+-terminus is in the extracellular space and the COO−-terminus is cytosolic. Each Siglec contains an N-terminal V-type immunoglobulin domain (Ig domain) which acts as the binding receptor for sialic acid. These lectins are placed into the group of I-type lectins because the lectin domain is an immunoglobulin fold. All Siglecs are extended from the cell surface by C2-type I... | |||
TMPK-00352 |
Siglec-4a/MAG Protein, Human, Recombinant (His & Avi), Biotinylated
S-MAG,MAG,GMA,Siglec-4a,Sigle... |
Human | HEK293 Cells |
Siglec-4a, also known as Myelin-Associated Glycoprotein (MAG), is a type I transmembrane glycoprotein belonging to the Siglec family, a subgroup of the Ig superfamily. Adhesion molecule that mediates interactions between myelinating cells and neurons by binding to neuronal sialic acid-containing gangliosides and to the glycoproteins RTN4R and RTN4RL2 (By similarity). | |||
TMPJ-01187 |
Siglec-E Protein, Mouse, Recombinant (hFc)
SiglecE,Siglec-E |
Mouse | HEK293 Cells |
Siglecs are sialic acid specific I‑type lectins that are characterized by an extracellular domain (ECD) with an N‑terminal Ig‑like V‑set domain followed by varying numbers of Ig‑like C2‑set domains. Mouse Siglec‑E, also known as Myeloid Inhibitory Siglec (MIS), is an 80 ‑ 85 kDa member of the CD33‑related subfamily of Siglecs. Rodent and primate Siglec gene families have significantly diverged, and Siglec‑9 is the most likely human ortholog of mouse Siglec‑E. Siglec‑E is expressed as a heavily N... | |||
TMPJ-01397 |
Siglec-7 Protein,Human,Recombinant(aa 19-353, His)
AIRM1,p75/AIRM1,CD328 antigen,CD3... |
Human | HEK293 Cells |
Siglecs (sialic acid binding Ig-like lectins) are I-type (Ig-type) lectins belonging to the Ig superfamily. They are characterized by an N-terminal Ig-like V-type domain which mediates sialic acid binding, followed by varying numbers of Ig-like C2-type domains. Eleven human Siglecs have been cloned and characterized. Human Siglec-7 encodes a 467 amino acid (aa) polypeptide with a hydrophobic signal peptide, an N-terminal Ig-like V-type domain, two Ig-like C2-type domains, a transmembrane region ... | |||
TMPJ-00537 |
Siglec-3/CD33 Protein, Human, Recombinant (hFc & His)
Myeloid Cell Surface Antigen CD33,CD33, |
Human | HEK293 Cells |
CD33 is a type I Lectin belonging to the Ig superfamily. CD33 contains an N terminal Ig like V type domain, which mediates sialic acid binding, followed by one Ig like C2 type domain, a transmembrane region and a cytoplasmic tail containing two conserved immunoreceptor tyrosine based inhibition motifs (ITIMs). Eleven human Siglecs have been characterized. Siglecs 5 to 11 share a high degree of sequence similarity with CD33/Siglec3 both in their extracellular and intracellular regions. They are c... |