Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-01584 |
PR-Set7 Protein, Human, Recombinant
SET8,SET07,PR-Set7,S... |
Human | E. coli |
KMT5A (known as PR-Set7/9, SETD8 and SET8), a member of the SET domain containing methyltransferase family specifically targeting H4K20 for methylation, has been implicated in multiple biological processes. Inhibition of KMT5A attenuated proliferation and induced apoptosis. Elevated KMT5A expression was significantly correlated with extrathyroidal extension, lymph node metastasis and advanced pathological stage of papillary thyroid cancer. KMT5A may be a novel oncogenic factor, specifically a re... |