Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T74756 |
SDH-IN-2
|
Antifungal | Microbiology/Virology |
SDH-IN-2 是一种有效的琥珀酸脱氢酶 (SDH) 抑制剂,IC50 为 0.55 μg/mL。SDH-IN-2 具有抗真菌活性,抑制植物病原真菌的平均 EC50 值为 3.82-9.81 μg/mL | |||
T37469 |
Sitamaquine tosylate
|
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Sitamaquine is an antileishmanial agent.1It is active againstL. donovani,L. infantum,L. mexicana,L. braziliensis, andL. tropica(EC50s = 9.5-19.8 μM). It inhibits mitochondrial complex II, also known as succinate dehydrogenase (SDH), in a cell-free assay when used at concentrations ranging from 10 to 200 μM.2Sitamaquine (100 μM) increases intracellular levels of reactive oxygen species (ROS) and decreases intracellular ATP levels, as well as induces phosphatidylserine externalization, chromatin f... |