Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
TP2115 |
SAH-EZH2
|
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EZH2/EPP interaction inhibitor (Kd = 320 nM). Suppresses EZH2 expression and H3K27 trimethylation by PCR2 complex. Arrests proliferation and induces monocyte to macrophage differentiation of MLL-AF9 leukemia cell line. |