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Cat. No.	Product Name	Target	Signaling Pathways
T70686	HJC-0123
	Downregulate phosphorylation of STAT3, increase the expression of cleaved caspase-3, inhibit cell cycle progression and promote apoptosis in breast and pancreatic cancer cells with low micromolar to nanomolar IC50 values. Furthermore, HJC-0123 significantly suppressed estrogen receptor (ER)-negative breast cancer MDA-MB-231 xenograft tumor growth in vivo (p.o.), indicating its great potential as an efficacious and orally bioavailable drug candidate for human cancer therapy.
T70688	S 0960
	S 0960 is a dimeric bile acid analogue that acts as a specific inhibitor of the apical sodium-dependent bile salt transporter (ASBT) in the ileum.