Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T70839 |
S 14063
|
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S 14063 is a potent 5-HT1A receptor antagonist devoid of beta-adrenoceptor blocking properties. | |||
T70837 | Rimegepant sulfate hydrate | ||
Rimegepant, also known as BMS-927711 and BHV-3000, is a potent, selective, competitive, and orally active calcitonin gene-related peptide (CGRP) antagonist in clinical trials for treating migraines. Rimegepant has shown in vivo efficacy without vasoconstriction effect. BMS-927711 is superior to placebo at several different doses (75 mg, 150 mg, and 300 mg) and has an excellent tolerability profile. |