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Cat. No.	Product Name	Target	Signaling Pathways
T34467	S 75 S75,S-75
	S 75 is a compound with radiation protective action.
T80363	Maximin 41
	Maximin 41是一种具有针对S. aureus抗菌活性（MIC: 75 μg/mL）的抗菌肽，同时对人红细胞展现溶血活性。
T66145	(S)-2-(((Benzyloxy)carbonyl)amino)-2-cyclohexylacetic acid
	(S)-2-(((Benzyloxy)carbonyl)amino)-2-cyclohexylacetic acid 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T66145，CAS号为 69901-75-3。
T66649	(S)-1-Phenyl-1,2,3,4-tetrahydroisoquinoline
	(S)-1-Phenyl-1,2,3,4-tetrahydroisoquinoline 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T66649，CAS号为 118864-75-8。
T65545	(S)-2-(((Benzyloxy)carbonyl)amino)-3-(tert-butoxy)propanoic acid
	(S)-2-(((Benzyloxy)carbonyl)amino)-3-(tert-butoxy)propanoic acid 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T65545，CAS号为 1676-75-1。
T65861	(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(o-tolyl)propanoic acid
	(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(o-tolyl)propanoic acid 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T65861，CAS号为 211637-75-1。
T80364	Maximin 45
	Maximin 45为一种具备抗菌特性的肽类化合物，针对S. aureus、E. coli、B. subtilis展现出了抗菌活性（MIC分别为4.7、9.4、75 μg/mL），同时，Maximin 45对人类和兔子红细胞显示出溶血活性。
T35759	Cardol triene
	Cardol triene is a phenol found in cashew nut shell liquid that competitively and irreversibly inhibits mushroom tyrosinase (IC50 = 22.5 μM). It is schistosomicidal, killing 25, 75, and 100% of S. mansoni worms after 24 hours when used at concentrations of 50, 100, or 200 μM, respectively. It has been used as a starting material for the synthesis of bis-benzoxazines.
T62509	Antitumor agent-74
	Antitumor agent-74 是一种喹唑啉衍生物，是一种抗肿瘤剂。Antitumor agent-74 与区域同分异构体 Antitumor agent-75 (compound 14 da) (mriBIQ 13da/14da) 联合使用表现出更强的肿瘤抑制效果。其中 mriBIQ 13da/14da 能够抑制 DNA 合成，将细胞周期阻滞在 S 期，并诱导线粒体凋亡。
T83807	Rp-Adenosine-5'-O-(1-thiotriphosphate) sodium Rp-ATP-α-S
	Rp-Adenosine-5'-O-(1-thiotriphosphate)（Rp-ATP-α-S）是一种含硫核苷酸衍生物ATP-α-S的异构体，同时也是嘌呤P2Y1受体的激动剂。在表达人类P2Y1受体的HEK293细胞中，Rp-ATP-α-S能增加钙的动员（EC50 = 75 nM）。该化合物与洗涤的人类孤立血小板结合（Ki = 156 nM），抑制由ADP引发的人类富血小板血浆（PRP）的聚集（pA2 = 4.74），并且能够抑制前列腺素E1（PGE1）在人类孤立PRP中引发的cAMP产生（pA2 = 5.26）。同时，Rp-ATP-α-S还能引起用氨基甲酰胆碱预先缩紧的豚鼠结肠条带的松弛（EC50 = 56 nM）。此外，Rp-ATP-α-S已经被用于合成被细菌核糖开关识别的环状二核苷酸。
T35855	AAA
	AAA is an antagonist of G protein-coupled receptor 75 (GPR75).1It increases basal GPR75 protein levels and inhibits 20-HETE-induced reductions in GPR75 protein levels in PC3 cells. AAA (5 and 10 μM) also reduces 20-HETE-induced phosphorylation of EGFR, NF-κB, and Akt in, and cell migration of, PC3 cells.In vivo, AAA (10 mg/kg per day) reduces systolic blood pressure, albuminuria, renal angiotensin II levels, and cardiac hypertrophy in a Cyp1a1-Ren-2 transgenic rat model of malignant hypertension...
T36241	Arecaidine propargyl ester (hydrobromide)
	Arecaidine propargyl ester is an agonist of M2muscarinic acetylcholine receptors (mAChRs).1It selectively binds to M2over M1, M3, M4, and M5mAChRs in CHO cells expressing the human receptors (Kis = 0.0871, 1.23, 0.851, 0.977, and 0.933 μM, respectively). Arecaidine propargyl ester induces contractions in isolated guinea pig atrium (pD2= 8.67). It induces apoptosis and the production of reactive oxygen species (ROS) in U87 and U251 glioblastoma cells when used at a concentration of 100 μM.2Arecai...
T35671	Salazinic Acid
	Salazinic acid is a depsidone lichen metabolite that has been found in P. sulcata.1 It is active against B. cereus, B. subtilis, S. aureus, P. aeruginosa, S. typhimurium, C. albicans, and A. niger in vitro (MICs = 3.9-30.8 mM). Salazinic acid is cytotoxic to MM98, A431, and HaCaT cells in crystal violet (EC50s = 159, 2,870, and 48 μM, respectively) and neutral red uptake assays (EC50s = 1,925, 1,913, and 907 μM, respectively).2 It increases the wound closure rate in scratch-wounded HaCaT monolay...
T37898	UDP-α-D-Glucose (sodium salt hydrate)
	UDP-α-D-Glucose is an endogenous nucleotide sugar involved in glycosyltransferase reactions in metabolism. It has been shown to bind the P2Y14receptor (EC50= 0.35 μM), an atypical P2Y receptor involved in the activation of dendritic cells and glial cells.1It can also bind to and activate GPR17, inducing oligodendrocyte differentiation at a maximal concentration of 100 μM.2 1.Jacobson, K.A., Ivanov, A.A., de Castro, S., et al.Development of selective agonists and antagonists of P2Y receptorsPurin...
T37702	Pancuronium (bromide hydrate)
	Pancuronium is an aminosteroid antagonist of muscle-type nicotinic acetylcholine receptors (nAChRs) with an IC50value of 14.8 nM using patch clamp electrophysiology in BOSC23 cells expressing mouse nAChRs.1It acts as a non-depolarizing neuromuscular blocking agent.2Pancuronium enhances anesthesia induced by isoflurane , reducing immobilization with an ED50value of 1.62 μg/kg.3 1.Liu, M., and Dilger, J.P.Site selectivity of competitive antagonists for the mouse adult muscle nicotinic acetylcholin...
T37187	D-erythro/L-threo Lysosphingomyelin (d18:1) D-erythro/L-threo Lysosphingomyelin (d18:1)
	Lysosphingomyelin is an endogenous bioactive sphingolipid and a constituent of lipoproteins.1,2It is produced by the removal of the acyl group from sphingomyelin by a deacylase and acts as a precursor in the biosynthesis of sphingosine-1-phosphate . D-erythroLysosphingomyelin is an agonist of the S1P receptors S1P1, S1P2, and S1P3(EC50s = 167.7, 368.1, and 482.6 nM, respectively, for the human receptors).3It is also an agonist of the orphan receptor ovarian cancer G protein-coupled receptor 1 (O...

化合物

Cat.No: T34467

Synonym: S75,S-75

Cat.No: T80363

(S)-2-(((Benzyloxy)carbonyl)amino)-2-cyclohexylacetic acid

Cat.No: T66145

(S)-1-Phenyl-1,2,3,4-tetrahydroisoquinoline

Cat.No: T66649

(S)-2-(((Benzyloxy)carbonyl)amino)-3-(tert-butoxy)propanoic acid

Cat.No: T65545

(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(o-tolyl)propanoic acid

Cat.No: T65861

Cat.No: T80364

Cat.No: T35759

Antitumor agent-74

Cat.No: T62509

Rp-Adenosine-5'-O-(1-thiotriphosphate) sodium

Cat.No: T83807

Synonym: Rp-ATP-α-S

Cat.No: T35855

Arecaidine propargyl ester (hydrobromide)

Cat.No: T36241

Cat.No: T35671

UDP-α-D-Glucose (sodium salt hydrate)

Cat.No: T37898

Pancuronium (bromide hydrate)

Cat.No: T37702

D-erythro/L-threo Lysosphingomyelin (d18:1)

Cat.No: T37187

Synonym: D-erythro/L-threo Lysosphingomyelin (d18:1)

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