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Cat. No. Product Name Target Signaling Pathways
T69966 Roxadustat-d5

Roxadustat-d5 is intended for use as an internal standard for the quantification of roxadustat by GC- or LC-MS. Roxadustat is an inhibitor of hypoxia-inducible factor prolyl hydroxylase (HIF-PH; IC50s = 1.4, 1.26, and 1.32 µM for HIF-PH1, HIF-PH2, and HIF-PH3, respectively). It is selective for HIF-PH over other 2-oxoglutarate-dependent dioxygenases, including lysine-specific demethylase 5A (KDM5A), KDM5B, -5C, -5D, and -6B (IC50s = >100 µM for all). Roxadustat (10-200 µM) stabilizes HIF-1α and ...
T69965 TP1287

TP-1287 is an oral phosphate prodrug of the CDK9 inhibitor, alvocidib.

化合物

Roxadustat-d5
Cat.No: T69966
Synonym:
Target:
TP1287
Cat.No: T69965
Synonym:
Target:
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