Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
TP1701 |
RC-3095 TFA
RC-3095 (TFA) |
Bombesin Receptor | GPCR/G Protein |
RC-3095 TFA (RC-3095(TFA)) 是蛙皮素/胃泌素释放肽受体选择性拮抗剂。它能降低关节炎小鼠的胃氧化损伤,从而发挥保护作用。 | |||
TP1470 |
RC-3095
|
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RC-3095, a selective GRPR antagonist, has been shown to have anti-inflammatory properties in different models of inflammation. | |||
TP2153 |
RC-3095 acetate
|
Others | Others |
RC-3095 acetate is an antagonist of bombesin/gastrin-releasing peptide receptor (GRPR). It exerts protective effects by reducing gastric oxidative injury in the arthritic mice. | |||
T35669 |
Neuromedin C (trifluoroacetate salt)
|
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Neuromedin C is a bombesin-like neuropeptide that stimulates uterine smooth muscle contraction and the release of gastrin , somatostatin, and amylase in rats. Neuromedin C is a truncated form of gastrin-releasing peptide corresponding to the GRP amino acids 18-27. It inhibits GRP and bombesin binding to rat pancreatic membranes (IC50s = 0.4 and 2.2 nM, respectively), which can be reduced by sodium chloride and guanylyl imidodiphosphate . Neuromedin C induces scratching and mast cell degranulatio... |