Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T16701 |
QCA570
|
Others | Others |
QCA570 is an effective BET degrader based on PROTAC (IC50: 10 nM for BRD4 BD1 Protein). | |||
T39679 |
Lenalidomide-I
|
||
Lenalidomide-I (Compound 72) is a derivative of the cereblon (CRBN) ligand, Lenalidomide, with affinity for E3 ubiquitin ligase. It facilitates the recruitment of CRBN protein. Lenalidomide-I can be utilized in PROTACs, such as the PROTAC BET degrader QCA570, by linking it to the targeted protein ligand through a linker. |