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Cat. No.	Product Name	Target	Signaling Pathways
T37919	Prostaglandin F1α PGF1α,Prostaglandin F1α
	Prostaglandin F1α (PGF1α) is the putative metabolite of dihomo-γ-linolenic acid (DGLA) via the cyclooxygenase (COX) pathway. Both PGF1α and PGF2α have been shown to act as priming pheromones for male Atlantic salmon with a threshold concentration of 10-11 M. [1] PGF1α binds to the ovine corpus luteum FP receptor at only 8% of the relative potency of PGF2α. [2] It is only half as active as PGF2α in inducing human respiratory smooth muscle contractions in vitro. [3]
T36162	8-iso Prostaglandin F1α 8-iso Prostaglandin F1α
	8-iso PGF1α is an isoprostane that was first identified in human semen. It is a member of the isoprostane family, which are eicosanoids of non-cyclooxygenase origin. 8-iso PGF1α is present along with its 19-hydroxy congener at 5-10 μg/ml of seminal plasma.
T36771	11-deoxy Prostaglandin F1α 11-deoxy Prostaglandin F1α
	11-deoxy PGF1α is a synthetic analog of PGF1α. In whole animal studies, a dose of 32 mg/kg inhibited gastric acid secretion by 35%. 11-deoxy PGF1α is also known to cause rat uterine contractions at a dose 0.3 times that of PGF1α. It also exhibits vasopressor and bronchoconstrictor activities at about half the potency of PGF2α in guinea pigs.
T37990	15-keto Prostaglandin F1α 15-keto Prostaglandin F1α
	15-keto PGF1α is the initial metabolite of PGF1α via 15-hydroxy PGDH. In mammals, oxidation of C-15 markedly attenuates receptor binding and activity. In fish, the 15-keto compounds serve as post-ovulatory pheromones and are more active than the parent prostaglandins.
T36724	6,15-diketo-13,14-dihydro Prostaglandin F1α 6,15-diketo-13,14-dihydro Prostaglandin F1α
	6,15-diketo-13,14-dihydro PGF1α is a metabolite of PGI2. It was shown to enhance intracellular cAMP and cholesterol catabolism in bovine arterial smooth muscle cells.
T36148	13,14-dihydro-15-keto Prostaglandin F1α 13,14-dihydro-15-keto Prostaglandin F1α
	13,14-dihydro-15-keto Prostaglandin F1α (13,14-dihydro-15-keto PGF1α) is a metabolite of PGF1α that has been reported in the rat stomach. The measurement of 13,14-dihydro-15-keto PGF1α can be used as a marker of the in vivo production of PGF1α.

化合物

Prostaglandin F1α

Cat.No: T37919

Synonym: PGF1α,Prostaglandin F1α

8-iso Prostaglandin F1α

Cat.No: T36162

Synonym: 8-iso Prostaglandin F1α

11-deoxy Prostaglandin F1α

Cat.No: T36771

Synonym: 11-deoxy Prostaglandin F1α

15-keto Prostaglandin F1α

Cat.No: T37990

Synonym: 15-keto Prostaglandin F1α

6,15-diketo-13,14-dihydro Prostaglandin F1α

Cat.No: T36724

Synonym: 6,15-diketo-13,14-dihydro Prostaglandin F1α

13,14-dihydro-15-keto Prostaglandin F1α

Cat.No: T36148

Synonym: 13,14-dihydro-15-keto Prostaglandin F1α

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