Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T38576 |
Propargyl-PEG1-THP
Propargyl-PEG1-THP |
||
Propargyl-PEG1-THP is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells. | |||
T16614 |
Propargyl-PEG4-acid
|
Others | Others |
Propargyl-PEG4-acid is a PEG-based PROTAC linker can be used in the synthesis of BTK-IAP PROTACs Ibrutinib -based PROTAC 2 and an analogue PROTAC 3. PROTAC 3 causes BTK degradation with a DC50 of 200 nM in THP-1 cells[1]. |