Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T16589 |
Propargyl-PEG1-SS-PEG1-acid
|
Others | Others |
Propargyl-PEG1-SS-PEG1-acid is a two-unit polyethylene glycol (PEG) linker that is cleavable and commonly employed in the synthesis of antibody-drug conjugates (ADCs) [1]. | |||
T16583 |
Propargyl-PEG1-acid
|
Others | Others |
Propargyl-PEG1-acid, a PEG-based PROTAC linker, enables the synthesis of BTK-CRBN PROTACs, specifically Ibrutinib-based PROTAC 4 and PROTAC 5. At a concentration of 10 μM, PROTAC 5 facilitates the degradation of BTK and induces the degradation of CSK, LYN, and LAT2[1]. |