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Cat. No. Product Name Target Signaling Pathways
T62205 Pparδ agonist 7

Pparδ agonist 7 是一种 Pparδ 的有效激动剂。其中过氧化物酶体增殖物激活受体 (PPAR) 属于核内受体转录因子超家族,在体内代谢稳态、炎症、细胞生长和分化的调节中发挥着关键作用。Pparδ agonist 7 对非酒精性脂肪肝 (NAFLD) 表现出研究潜力。
T61417 PPARγ agonist 7

PPARγ agonist 7 (Compound 3a) is a highly potent and selective agonist of the peroxisome proliferator-activated receptor gamma (PPARγ). It specifically stimulates adiponectin production in human bone marrow mesenchymal stem cells (hBM-MSCs), making it an innovative full agonist of PPARγ with an EC 50 value of 4.34 μM [1].
T35799 MBX-8025 (sodium salt)

MBX-8025 is an agonist of peroxisome proliferator-activated receptor δ (PPARδ).1 It is greater than 750- and 2,500-fold selective for PPARδ over PPARα and PPARγ. MBX-8025 (10 mg/kg per day for eight weeks) reduces increases in fasting blood glucose and serum insulin levels, and decreases insulin resistance in Alms1 mutant (foz/foz) mice fed an atherogenic diet as a model of diet-induced obesity, type 2 diabetes, and non-alcoholic steatohepatitis (NASH).2 It also decreases serum alanine transamin...

化合物

Pparδ agonist 7
Cat.No: T62205
Synonym:
Target:
PPARγ agonist 7
Cat.No: T61417
Synonym:
Target:
MBX-8025 (sodium salt)
Cat.No: T35799
Synonym:
Target:
TargetMol Loading
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