Cat. No. | Product Name | Target | Signaling Pathways |
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T39883 |
Polyketide synthase 13-IN-1
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Polyketide synthase 13-IN-1 (compound 32) is a polyketide synthase 13 inhibitor. | |||
T61598 | Polyketide synthase 13-IN-2 | ||
Polyketide synthase 13-IN-2 (comp 42) is a potent inhibitor of polyketide synthase 13 in Mycobacterium tuberculosis. It demonstrates a minimum inhibitory concentration (MIC) of 0.25 μg/mL [1]. | |||
T40520 |
Thiophene-2
Thiophene-2,TP2 |
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Thiophene-2 (TP2) is a targeted inhibitor of polyketide synthase 13 (Pks13), specifically designed to disrupt mycolic acid biosynthesis. By doing so, it effectively induces rapid cell death in mycobacteria. Thiophene-2 demonstrates notable anti-tuberculosis activity and exhibits a minimum inhibitory concentration (MIC) value of 1 μM against Mycobacterium tuberculosis. |