Cat. No. | Product Name | Target | Signaling Pathways |
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T71558 | Pim-IN-14j | ||
Pim-IN-14j is a potent, highly selective, and orally bioavailable inhibitor of PIM-1 kinases. | |||
T71556 |
MK-1496
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MK1496 is a n orally bioavailable Polo-like kinase 1 (Plk1) inhibitor with potential antineoplastic activity. Polo-like kinase 1 inhibitor MK1496 selectively inhibits Plk1, inducing selective G2/M arrest followed by apoptosis in a variety of tumor cells while causing reversible cell arrest at the G1 and G2 stage without apoptosis in normal cells. Plk1, named after the polo gene of Drosophila melanogaster, is a serine/threonine protein kinase involved in regulating mitotic spindle function in a n... |