Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
TP1137L |
Pancreatic Polypeptide (human) acetate
|
Neuropeptide Y Receptor | GPCR/G Protein; Neuroscience |
Pancreatic Polypeptide (human) acetate 是一种 C 末端酰胺化的 36 个氨基酸肽,可作为神经肽 Y (NPY) Y4/Y5 受体激动剂。 | |||
TP1137 |
Pancreatic Polypeptide, human
Human pancreatic polypeptide |
||
Endogenous high affinity agonist for human NPY Y4 receptor (Ki = 0.056 nM). Believed to play an important role in the function of the gastrointestinal tract. | |||
T75787 |
Amylin, amide, human TFA
|
||
Amylin, amide, human TFA 是一种含有37个氨基酸的胰腺多肽,与胰岛素共同分泌,对代谢和维持葡萄糖稳态具有重要作用。该化合物能够抑制胰高血糖素的分泌,延缓胃排空速度,同时作为增加饱腹感的因子。 | |||
T36864 |
GRP (human) (trifluoroacetate salt)
|
||
Gastrin-releasing peptide (GRP) is a neuropeptide that stimulates gastrin release. It binds to (Ki = 300 nM) and stimulates amylase secretion in rat pancreatic AR42J cells (EC50 = 0.3 nM). GRP increases proliferation of human liver carcinoma HepG2 and MHCC97H cells but does not affect the proliferation of normal HL-7702 liver cells at a concentration of 1 nM. In vivo, GRP (0.35 nmol/kg/h) increases both pancreatic exocrine secretion and pancreatic polypeptide (PP) release in rats. It dose-depend... |