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Cat. No. Product Name Target Signaling Pathways
T12555 PROTAC FLT-3 degrader 1

Others Others
PROTAC FLT-3 degrader 1 is a PROTAC FLT-3 degrader of internal tandem duplication (ITD)(IC50 0.6 nM),with anti-proliferative activity.
T74707 PROTAC FLT3/CDK9 degrader-1

PROTACFLT3/CDK9 degrader-1 是一种有效的FLT3和CDK9双PROTAC 降解剂。PROTACFLT3/CDK9 degrader-1 诱导细胞凋亡 (Apoptosis) 并有效降解靶蛋白FLT3和 CDK9。PROTACFLT3/CDK9 degrader-1具有研究 FLT3-ITD 突变型 AML 的潜力。
T39818 Desmorpholinyl Quizartinib-PEG2-COOH

Desmorpholinyl Quizartinib-PEG2-COOH

Desmorpholinyl Quizartinib-PEG2-COOH is a compound featuring an FLT-3 ligand and a PEG-based PROTAC linker. It is employed in the synthesis of PROTAC FLT-3 degrader 1, which serves as a degrader for the FLT-3 internal tandem duplication (ITD) through PROTAC technology. The degrader exhibits an IC50 of 0.6 nM.

化合物

PROTAC FLT-3 degrader 1
Cat.No: T12555
Synonym:
Target: Others
PROTAC FLT3/CDK9 degrader-1
Cat.No: T74707
Synonym:
Target:
Desmorpholinyl Quizartinib-PEG2-COOH
Cat.No: T39818
Synonym: Desmorpholinyl Quizartinib-PEG2-COOH
Target:
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