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Cat. No. Product Name Target Signaling Pathways
T40075 PROTAC BRD4 Degrader-13

PROTAC BRD4 Degrader-13

PROTAC BRD4 Degrader-13 (compound 9d) is a bioactive compound that functions as a proteolysis targeting chimera (PROTAC), linking ligands for von Hippel-Lindau and BRD4 proteins. In the context of PC3 prostate cancer cells, this compound effectively degrades the BRD4 protein through conjugation with STEAP1 and CLL1 antibodies. The degradation of BRD4 protein is achieved with remarkable potency, exhibiting a DC 50 of 0.025 nM and 6.0 nM when combined with STEAP1 and CLL1 antibodies, respectively.

化合物

PROTAC BRD4 Degrader-13
Cat.No: T40075
Synonym: PROTAC BRD4 Degrader-13
Target:
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