Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-01769 |
4EBP1 Protein, Human, Recombinant (His)
4E-BP1,eukaryotic translation in<... |
Human | E. coli |
The translational suppressor eIF4E binding protein-1, 4E-BP1 functions as a key regulator in cellular growth, differentiation, apoptosis and survival. The Eif4ebp1 gene, encoding 4E-BP1, is a direct target of a transcription factor activating transcription factor-4 (ATF4), a master regulator of gene expression in stress responses. 4E-BP1 is characterized by its capacity to bind specifically to eIF4E and inhibit its interaction with eIF4G. Phosphorylation of 4E-BP1 regulates eIF4E availability, a... |