Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T24623 |
PF-06807656
PF 06807656 |
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PF-06807656 is insensitive to the introduction of the N171D mutation in the ROMK conduction pore that greatly diminishes the activity of other small-molecule inhibitors. PF-06807656 is an effective ROMK inhibitor (Tl+ flux IC50 = 160 nM). |