Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T12673L |
PF-06250112
|
BTK | Angiogenesis; Tyrosine Kinase/Adaptors |
PF-06250112 is an effective and highly selective BTK inhibitor (IC50: 0.5 nM. PF-06250112 displays an inhibitory effect toward BMX nonreceptor tyrosine kinase and TEC (IC50s: 0.9 nM and 1.2 nM, respectively). | |||
T12673 | (Rac)-PF-06250112 | Others | Others |
(Rac)-PF-0625011 是 PF-06250112 的外消旋体。PF-06250112 是一种新型有效的、高度选择性、口服有效的 BTK 抑制剂。PF-06250112 对 BMX 非受体酪氨酸激酶和 TEC 同样有抑制作用。 |