Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T27734 |
KM-003 (sulfite)
KM 003,P-552,KM003,P552,P 552,KM-003 |
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KM-003, a sodium channel blocker, is used potentially for the treatment of cystic fibrosis. | |||
T69052 | P552-02 free base | ||
P552-02, also known as KM-003, PS 552-02, or 552-02, is a sodium channel blocker potentially for the treatment of cystic fibrosis. | |||
T35712 |
Debutyldronedarone hydrochloride
SR35021 hydrochloride |
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N-Desbutyl dronedarone is an active metabolite of the antiarrhythmic agent dronedarone .1,2,3It is formed from dronedarone by cytochrome P450s (CYPs) and monoamine oxidase (MAO) in human hepatocyte preparations.4N-Desbutyl dronedarone inhibits the binding of 3,3’,5-triiodo-L-thyronine to the thyroid hormone receptors TRα1and TRβ1(IC50s = 59 and 280 μM for the chicken and human receptors, respectively).1It inhibits CYP2J2-mediated formation of 14,15-EET from arachidonic acid and soluble epoxide h... |