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Search Results for " oseltamivir "

13

抑制剂 & 化合物

1

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T5186L	Oseltamivir

T5186	Oseltamivir acid GS 4071,oseltamivir carboxylate,奥斯他伟酸,Ro 64-0802	Influenza Virus; Drug Metabolite	Metabolism; Microbiology/Virology
	Oseltamivir acid (GS 4071) 是Oseltamivir phosphate 的活性代谢产物，是一种有效的流感病毒神经氨酸酶抑制剂和 GS4071 的前药。
T1486	Oseltamivir phosphate GS 4104,磷酸奥司他韦	Influenza Virus	Microbiology/Virology
	Oseltamivir phosphate (GS 4104) 是一种神经氨酸酶抑制剂，可研究流感。
T60663L	Oseltamivir acid methyl ester hydrochloride	Others	Others
	Oseltamivir acid methyl ester hydrochloride 是奥司他韦酸的前体形式。它通过羧酸酯酶1 (CES1) 转化为奥司他韦酸。
T33827	Oseltamivir carboxylate HCl Oseltamivir carboxylate(HCI),GS4071 HC,Oseltamivir carboxylate HCI,Oseltamivir carboxylate hydrochloride,Ro 64-0802 hydrochloride
	Oseltamivir carboxylate is an active metabolite of oseltamivir phosphate (Tamiflu).
T37510	Oseltamivir-acetate
	Oseltamivir-acetate, an impurity of Oseltamivir, is a recommended neuraminidase inhibitor for both the treatment and prophylaxis of influenza A and B[1][2].
T60663	Oseltamivir acid methyl ester	Others	Others
	Oseltamivir acid methyl ester 是Oseltamivir acid 的前体形式，可通过羧酸酯酶1 (CES1) 转化为Oseltamivir acid。Oseltamivir acid 是神经氨酸酶抑制剂和抗病毒剂。
T24428	M090 M 090,M-090
	M090 is a potent inhibitor against amantadine-resistant viruses, including the 2009 H1N1 pandemic strains and oseltamivir-resistant viruses.
T61557	Influenza A virus-IN-4
	Influenza A virus-IN-4 (compound 23b), a derivative of Oseltamivir, is a highly effective neuraminidase inhibitor. It exerts potent inhibitory effects on influenza viruses [1].
T72717	Anti-IAV agent 1
	Anti-IAV agent 1-1a) 是一种口服抗甲型流感病毒(IAV)剂，对IAV H1N1及Oseltamivir抗性IAV H1N1的IC50值分别是0.03μM与0.06μM。
T83046	Anti-Influenza agent 5	Influenza Virus	Microbiology/Virology
	Anti-Influenza agent 5 (Compound IIB-2)为查耳酮类衍生物，具有抑制流感病毒核输出的活性。该化合物能有效抑制对Oseltamivir具有耐药性的病毒株，主要通过阻断流感病毒核蛋白输出作用来抑制病毒复制。
T37466	CAY10766
	CAY10766 is an antiviral compound.1It inhibits entry of influenza virus-like particles pseudotyped with hemagglutinin A (HA) from H5N1 influenza A virus into A549 cells (EC50= 0.24 μM). CAY10766 (1 μM) reduces H1N1 and H5N1 influenza A viral titers in infected MDCK cells. It also exhibits synergy with oseltamivir carboxylate in MDCK cells infected with the influenza A reporter PR8-NS1-Gluc virus.
T83742	SBP1 TFA Spike Binding Peptide 1
	Spike binding peptide 1 (SBP1) 为对应于血管紧张素转换酶2 (ACE2) 的第21至43位氨基酸的肽。已将脂质纳米粒子 (LNPs) 包裹的抗病毒化合物奥司他韦磷酸盐与SBP1结合并通过体外研究评估其控制释放奥司他韦磷酸盐的长期潜力。SBP1 (2%) 固定于交联的羟基丙烯酸酯和乙基黄原酸乙酯网络，提高了对严重急性呼吸系统冠状病毒2(SARS-CoV-2)刺突糖蛋白，亦称表面糖蛋白，的网络捕获效率。

化合物

Cat.No: T5186L

Oseltamivir acid

Cat.No: T5186

Synonym: GS 4071,oseltamivir carboxylate,奥斯他伟酸,Ro 64-0802

Target: Influenza Virus, Drug Metabolite

Oseltamivir phosphate

Cat.No: T1486

Synonym: GS 4104,磷酸奥司他韦

Target: Influenza Virus

Oseltamivir acid methyl ester hydrochloride

Cat.No: T60663L

Target: Others

Oseltamivir carboxylate HCl

Cat.No: T33827

Synonym: Oseltamivir carboxylate(HCI),GS4071 HC,Oseltamivir carboxylate HCI,Oseltamivir carboxylate hydrochloride,Ro 64-0802 hydrochloride

Oseltamivir-acetate

Cat.No: T37510

Oseltamivir acid methyl ester

Cat.No: T60663

Target: Others

Cat.No: T24428

Synonym: M 090,M-090

Influenza A virus-IN-4

Cat.No: T61557

Anti-IAV agent 1

Cat.No: T72717

Anti-Influenza agent 5

Cat.No: T83046

Target: Influenza Virus

Cat.No: T37466

Cat.No: T83742

Synonym: Spike Binding Peptide 1

Cat. No.	Product Name	Target	Signaling Pathways
TN4108	Ganoderic acid Z	Antifection	Microbiology/Virology
	The binding affinities of ganoderic acid DM and ganoderic acid Z (ÎGbind, -16.83 and-10.99 kcal mol-1) are comparable to that of current commercial drug oseltamivir (-23.62 kcal mol-1);Ganoderic acid DM is a potential source of anti-influenza ingredient, with novel binding pattern and advantage over oseltamivir, it has steric hindrance on the 150 cavity of N1 protein, and exerts activities across the H274Y and N294S mutations, is the attractive candidates of novel neuraminidase (NA) inhibitors....

天然产物

Ganoderic acid Z

Cat.No: TN4108

Target: Antifection

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