1
1
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T36398 |
Paclitaxel octadecanedioate
|
||
Paclitaxel octadecanedioate is a prodrug form of paclitaxel that is comprised of paclitaxel conjugated to 1,18-octadecanedioic acid.1 Unlike paclitaxel, it does not promote tubulin polymerization in vitro when used at a concentration of 10 μM. A 5:1 mixture of paclitaxel octadecanedioate:human serum albumin (HSA) is cytotoxic to HT-1080, PANC-1, and HT-29 cells (IC50s = 12, 2.48, and 8.62 nM, respectively). This mixture reduces tumor growth and increases survival in an HT-1080 mouse xenograft mo... |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T12287 |
Octadecanedioic acid
|
Endogenous Metabolite | Metabolism |
Octadecanedioic acid 是内源性代谢物的一种,是一种长链二羧酸,曾在雷氏综合征的血清游离脂肪酸中被发现。 |