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Cat. No. | Product Name | Target | Signaling Pathways |
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T73295 |
WNK1-IN-1
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WNK1-IN-1 是 WNK1的选择性抑制剂,IC50值为 1.6 μM。WNK1-IN-1 抑制 OSR1 磷酸化,IC50值为 4.3 μM。WNK1-IN-1 可用于血压调节和癌症的研究。 | |||
T29161 |
STOCK2S-26016
WNK IN B,WNK-IN-B,Compound B |
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WNK-IN-B is an inhibitor of Wnk signalling. WNK-IN-B is a cell-permeable diaminoacridine derivative that targets the CCT domain of SPAK and OSR1 via reversible binding. WNK-IN-B selectively suppress hypotonic shock-induced WNK signaling pathway activation |
Cat. No. | Product Name | Species | Expression System |
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TMPY-04460 |
OXSR1 Protein, Human, Recombinant (GST)
OSR1,oxidative stress responsive 1 |
Human | Baculovirus Insect Cells |
Oxidative stress-responsive 1 protein (OXSR1), also known as Serine/threonine-protein kinase OSR1, is a member of the Ser/Thr protein kinase family of proteins. OXSR1 regulates downstream kinases in response to environmental stress, and may play a role in regulating the actin cytoskeleton. OXSR1 is a 58 kDa protein of 527 amino acids that is widely expressed in mammalian tissues and cell lines. The amino acid (aa) sequence of the predicted OXSR1 protein is 39% identical to that of human SOK1. Of... |