Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-02798 |
NEIL1 Protein, Human, Recombinant (His)
NEI1,nei endonuclease VIII-like <... |
Human | E. coli |
NEIL1 is a member of DNA glycosylases. DNA glycosylases are a family homologous to the bacterial Fpg/Nei family. They play a role in base excision repair which is the mechanism by which damaged bases in DNA are removed and replaced. The first step of this process is catalyzed by DNA glycosylases. They remove the damaged nitrogenous base while leaving the sugar-phosphate backbone intact, creating an apurinic/apyrimidinic site, commonly referred to as an AP site. NEIL1 functions in base excision r... |