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Cat. No. | Product Name | Target | Signaling Pathways |
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T72137 |
Mitochondrial respiration-IN-3
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Mitochondrial respiration-IN-3 是 Dalfopristin 的氟衍生物。Mitochondrial respiration-IN-3 具有细胞膜渗透性。Mitochondrial respiration-IN-3 可以抑制胶质母细胞瘤干细胞的线粒体翻译 (mitochondrial translation)。Mitochondrial respiration-IN-3 可用于癌症的研究 | |||
T63538 |
8-Azido-ADP disodium
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8-Azido-ADP (disodium) 是一种线粒体腺嘌呤核苷酸易位的共价结合抑制剂,对ADP 诱导的线粒体呼吸的 4 到 3 正常转变表现出抑制作用。在光依赖反应中,8-Azido-ADP (disodium) 不可逆的抑制腺嘌呤核苷酸交换。 | |||
T37355 |
CAY10703
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Dichloroacetate (DCA) is an inhibitor of all pyruvate dehydrogenase kinase (PDHK) isoforms, which are enzymes that phosphorylate and inhibit PDH in mitochondria. Inhibition of PDHK shifts cell metabolism from glycolysis to mitochondrial glucose oxidation, an effect that has relevance to cancer, type 2 diabetes, and other diseases. CAY10703 is a DCA trimer that is at least 10-fold more cytotoxic against leukemia cell lines than DCA. It is approximately 3-fold less cytotoxic than DCA against perip... | |||
T37692 |
Piericidin B
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Piericidin B is a bacterial metabolite that has been found inS. mobaraensisand has insecticidal and antimicrobial activities.1,2,3It inhibits NADH oxidase activity in isolated bovine heart mitochondria and inhibits respiration in isolated rat liver mitochondria and isolated cockroach (P. americana) muscle mitochondria.2,3Topical application of piericidin B (4 μg/insect) induces mortality in 87.5% of houseflies (M. domestica).1It induces 93.3, 100, and 100% mortality in rice stem borer (C. simple... |
Cat. No. | Product Name | Target | Signaling Pathways |
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TN6608 |
Cyanidin-3-O-arabinoside chloride
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Cyanidin-3-O-arabinoside chloride has antioxidant activity. It reduces the peroxynitrite-induced suppression of mitochondrial respiration, DNA damage, PARS activation and vascular dysfunction in HUVECs. |