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Cat. No. Product Name Target Signaling Pathways
T12040 Milademetan

RAIN-32,DS-3032,DS3032b

Mdm2; Others Apoptosis; Others
Milademetan (DS-3032) 是一种具有口服活性和有效性的 MDM2 抑制剂,具有抗肿瘤活性,诱导 G1 细胞周期阻滞、衰老和凋亡。Milademetan 可用于研究急性髓系白血病和实体肿瘤。
T28038 Milademetan HCl (1398568-47-2 free base)

Milademetan HCl,DS3032,DS 3032,DS-3032,DS3032b,DS-3032b,DS 3032b

Milademetan is a potent and selective MDM2 inhibitor. MDM2 inhibitor DS-3032b binds to and prevents the binding of MDM2 protein to the transcriptional activation domain of the tumor suppressor protein p53 upon oral administration. By preventing this MDM2-p53 interaction, the proteosome-mediated enzymatic degradation of p53 is inhibited and the transcriptional activity of p53 is restored. This results in the restoration of p53 signaling and leads to the p53-mediated induction of tumor cell apopto...
T24466 Milademetan free base

DS3032B,DS-3032,DS3032,DS 3032,DS 3032B,DS-3032B

Milademetan (DS-3032b or DS-3032) is a potent and selective MDM2 inhibitor with potential antineoplastic activity. Milademetan (p.o.) binds to and prevents the binding of MDM2 protein to the transcriptional activation domain of the tumor suppressor protei
T73634 Milademetan tosylate hydrate

Milademetan (DS-3032) tosylate hydrate,一种特异性、具口服活性的MDM2抑制剂,主要研究用途包括急性髓系白血病和实体肿瘤。它能诱导G1细胞周期阻滞、衰老和凋亡。

化合物

Milademetan
Cat.No: T12040
Synonym: RAIN-32,DS-3032,DS3032b
Target: Mdm2, Others
Milademetan HCl (1398568-47-2 free base)
Cat.No: T28038
Synonym: Milademetan HCl,DS3032,DS 3032,DS-3032,DS3032b,DS-3032b,DS 3032b
Target:
Milademetan free base
Cat.No: T24466
Synonym: DS3032B,DS-3032,DS3032,DS 3032,DS 3032B,DS-3032B
Target:
Milademetan tosylate hydrate
Cat.No: T73634
Synonym:
Target:
TargetMol Loading
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