Cat. No. | Product Name | Target | Signaling Pathways |
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T71285 |
Metaxalone-d6
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Metaxalone-d6 is intended for use as an internal standard for the quantification of metaxalone by GC-or LC-MS. Metaxalone is a skeletal muscle relaxant. It inhibits the proliferation of, and induces apoptosis in, RAW 264.7 cells in vitro when used at concentrations ranging from 1 to 100 µM. Metaxalone also reduces LPS-induced increases in COX-1, COX-2, and NF-kB levels and inhibits LPS-induced production of TNF-α, IL-6, and prostaglandin E2 in RAW 264.7 cells. Formulations containing metaxalone ... | |||
T71283 |
JNJ-40929837
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JNJ-40929837 is an oral inhibitor of LTA4 hydrolase, which catalyzes LTB4 production. |