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Cat. No. Product Name Target Signaling Pathways
T27977 Manzamine A

Keramamine A

Manzamine A is a GSK-3 inhibitor and vacuolar ATPase uncoupler found in marine sponges. It inhibits autophagy and tumor growth in cancer models, suppresses foam cell formation in macrophages, prevents growth of gram negative and gram positive bacteria, an
T38441 Manzamine A hydrochloride

Manzamine A hydrochloride is an orally active beta-carboline alkaloid that exhibits specific inhibitory effects on GSK-3β (IC50 = 10.2 μM) and CDK-5 (IC50 = 1.5 μM). Additionally, it targets vacuolar ATPases, leading to the inhibition of autophagy in pancreatic cancer cells. Manzamine A hydrochloride possesses antimalarial and anticancer properties, and also demonstrates potent activity against HSV-1[4].

天然产物

Manzamine A
Cat.No: T27977
Synonym: Keramamine A
Target:
Manzamine A hydrochloride
Cat.No: T38441
Synonym:
Target:
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