Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-02044 |
SOD2 Protein, Human, Recombinant
superoxide dismutase 2, mitochondrial,IPOB,MNSOD,MVCD |
Human | E. coli |
Superoxide dismutases (SOD) are important anti-oxidant enzymes that guard against superoxide toxicity. In humans, as in all mammals and most chordates, three forms of superoxide dismutase (SOD) are present: SOD1 is located in the cytoplasm, SOD2 in the mitochondria, and SOD3 is extracellular. Mitochondrial superoxide dismutase [SOD; manganese SOD (MnSOD) or SOD2] neutralizes highly reactive superoxide radical (O•-2), the first member in the plethora of mitochondrial reactive oxygen species. | |||
TMPJ-00104 |
SOD2 Protein, Human, Recombinant (E. coli, His)
SOD2,Superoxide Dismutase [Mn] Mitochondrial |
Human | E. coli |
Superoxide Dismutase (SOD2) is a number of the iron/manganese superoxide dismutase family. SOD2 is a mitochondrial protein that forms a homotetramer and binds one manganese ion per subunit. The SOD2 protein transforms toxic superoxide and a byproduct of the mitochondrial electron transport chain into hydrogen peroxide and diatomic oxygen. Genetic variation in SOD2 is associated with microvascular complications of diabetes type 6 (MVCD6), idiopathic cardiomyopathy (IDC), sporadic motor neuron dis... |