Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T24489 |
MM-401
MM401 |
||
MM-401 is a specific inhibitor of histone H3K4 methyltransferase MLL1 activity that acts by reprogramming mouse epiblast stem cells to naive pluripotency. | |||
T75258 | MM-401 TFA | ||
MM-401 (TFA) 是一种针对MLL1 H3K4甲基转移酶的抑制剂,通过阻断MLL1与WDR5的相互作用,有效抑制MLL1活性,其IC50值为0.32 µM。此化合物能够诱导细胞周期停滞、凋亡及分化,主要用于MLL白血病的研究。 |